Publications médicales – 2019

• Pancreatic sphincterotomy improves pain symptoms due to branch-duct intrapapillary mucinous neoplasia without worrisome features: a multicenter study.

Gonzalez JM, Lorenzo D, Ratone JP, Culetto A, Maire F, Levy P, Giovannini M, Barthet M. Endosc Int Open. 2019 Sep;7(9):E1130-E1134. doi: 10.1055/a-0841-3385. Epub 2019 Aug 29. PMID: 31475230 

• Tumor growth rate as a metric of progression, response, and prognosis in pancreatic and intestinal neuroendocrine tumors.

Dromain C, Pavel ME, Ruszniewski P, Langley A, Massien C, Baudin E, Caplin ME; CLARINET Study Group.

BMC Cancer. 2019 Jan 14;19(1):66. doi: 10.1186/s12885-018-5257-x.

PMID: 30642293 

• Unmet Needs in Functional and Nonfunctional Pancreatic Neuroendocrine Neoplasms.

Jensen RT, Bodei L, Capdevila J, Couvelard A, Falconi M, Glasberg S, Kloppel G, Lamberts S, Peeters M, Rindi G, Rinke A, Rothmund M, Sundin A, Welin S, Fazio N; The ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):26-36. doi: 10.1159/000494258. Epub 2018 Oct 3.

PMID: 30282083

• Unmet Medical Needs in Pulmonary Neuroendocrine (Carcinoid) Neoplasms.

Baudin E, Hayes AR, Scoazec JY, Filosso PL, Lim E, Kaltsas G, Frilling A, Chen J, Kos-Kudła B, Gorbunova V, Wiedenmann B, Nieveen van Dijkum E, Ćwikła JB, Falkerby J, Valle JW, Kulke MH, Caplin ME; ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):7-17. doi: 10.1159/000493980. Epub 2018 Sep 24.

PMID: 30248673

• Unmet Needs in Appendiceal Neuroendocrine Neoplasms.

Toumpanakis C, Fazio N, Tiensuu Janson E, Hörsch D, Pascher A, Reed N, O Apos Toole D, Nieveen van Dijkum E, Partelli S, Rinke A, Kos-Kudla B, Costa F, Pape UF, Grozinsky-Glasberg S, Scoazec JY; The ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):37-44. doi: 10.1159/000493894. Epub 2018 Sep 20.

PMID: 30235454

• Colorectal Neuroendocrine Neoplasms: Areas of Unmet Need.

Ramage JK, Valle JW, Nieveen van Dijkum EJM, Sundin A, Pascher A, Couvelard A, Kloeppel G; the ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):45-53. doi: 10.1159/000493767. Epub 2018 Sep 16.

PMID: 30219817

• Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms.

Capdevila J, Bodei L, Davies P, Gorbounova V, Jensen RT, Knigge UP, Krejs GJ, Krenning E, O’Connor JM, Peeters M, Rindi G, Salazar R, Vullierme MP, Pavel ME; ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):18-25. doi: 10.1159/000493319. Epub 2018 Aug 28.

PMID: 30153686 Free Article

• Unmet Needs in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO G3).

Sorbye H, Baudin E, Borbath I, Caplin M, Chen J, Cwikla JB, Frilling A, Grossman A, Kaltsas G, Scarpa A, Welin S, Garcia-Carbonero R; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):54-62. doi: 10.1159/000493318. Epub 2018 Aug 28.

PMID: 30153658

• Unmet needs in the international neuroendocrine tumor (NET) community: assessment of major gaps from the perspective of patients, patient advocates and NET healthcare professionals.

Leyden S, Kolarova T, Bouvier C, Caplin M, Conroy S, Davies P, Dureja S, Falconi M, Ferolla P, Fisher G, Goldstein G, Hicks RJ, Lawrence B, Majima Y, Metz DC, O’Toole D, Ruszniewski P, Wiedenmann B, Hollander R; International Neuroendocrine Cancer Alliance (INCA).

Int J Cancer. 2019 Sep 11. doi: 10.1002/ijc.32678. [Epub ahead of print]

PMID: 31509608

• A randomized, open-label, phase 2 study of everolimus in combination with pasireotide LAR or everolimus alone in advanced, well-differentiated, progressive pancreatic neuroendocrine tumors: COOPERATE-2 trial.

Kulke MH, Ruszniewski P, Van Cutsem E, Lombard-Bohas C, Valle JW, De Herder WW, Pavel M, Degtyarev E, Brase JC, Bubuteishvili-Pacaud L, Voi M, Salazar R, Borbath I, Fazio N, Smith D, Capdevila J, Riechelmann RP, Yao JC.

Ann Oncol. 2019 Aug 13. pii: mdz219. doi: 10.1093/annonc/mdz219. [Epub ahead of print] 

PMID: 31407000

• The ENETS TNM staging and grading system accurately predict prognosis in patients with rectal NENs.

Capurso G, Gaujoux S, Pescatori LC, Panzuto F, Panis Y, Pilozzi E, Terris B, de Mestier L, Prat F, Rinzivillo M, Coriat R, Coulevard A, Delle Fave G, Ruszniewski P.

Dig Liver Dis. 2019 Aug 9. pii: S1590-8658(19)30713-3. doi: 10.1016/j.dld.2019.07.011. [Epub ahead of print]

PMID: 31405587

• Chemotherapy in resected neuroendocrine carcinomas of the digestive tract: a national study from the French Group of Endocrine Tumours (GTE).

Pellat A, Walter T, Augustin J, Hautefeuille V, Hentic O, Do Cao C, Lièvre A, Coriat R, Hammel P, Dubreuil O, Cohen R, Couvelard A, André T, Svrcek M, Baudin E, Afchain P.

Neuroendocrinology. 2019 Aug 21. doi: 10.1159/000502825. [Epub ahead of print]

PMID: 31430756

• How Does Chemoradiotherapy Following Induction FOLFIRINOX Improve the Results in Resected Borderline or Locally Advanced Pancreatic Adenocarcinoma? An AGEO-FRENCH Multicentric Cohort.

Pietrasz D, Turrini O, Vendrely V, Simon JM, Hentic O, Coriat R, Portales F, Le Roy B, Taieb J, Regenet N, Goere D, Artru P, Vaillant JC, Huguet F, Laurent C, Sauvanet A, Delpero JR, Bachet JB, Sa Cunha A.

Ann Surg Oncol. 2019 Jan;26(1):109-117. doi: 10.1245/s10434-018-6931-6. Epub 2018 Oct 25. PMID: 30362063

• Impact of needle-based confocal laser endomicroscopy on the therapeutic management of single pancreatic cystic lesions.

Palazzo M, Sauvanet A, Gincul R, Borbath I, Vanbiervliet G, Bourdariat R, Lemaistre AI, Pujol B, Caillol F, Palazzo L, Aubert A, Maire F, Buscail L, Giovannini M, Marque S, Napoléon B.

Surg Endosc. 2019 Aug 13. doi: 10.1007/s00464-019-07062-9. [Epub ahead of print] PMID: 31410626

• Extended Laparoscopic Central Pancreatectomy with Clamping of the Mesentericoportal Vein and Resection of the Splenic Vessels for a Large Solid Pseudopapillary Tumor.

Dokmak S, Aussilhou B, Paci M, Ftériche FS, Cros J, Maire F, Soubrane O, Sauvanet A.

Ann Surg Oncol. 2019 Oct;26(11):3709-3710. doi: 10.1245/s10434-019-07689-x. Epub 2019 Aug 12. PMID: 31407182

• Impact of peroral cholangioscopy on the management of indeterminate biliary conditions: a multicentre prospective trial.

Prat F, Leblanc S, Foissac F, Ponchon T, Laugier R, Bichard P, Maire F, Coumaros D, Charachon A, Vedrenne B, Boytchev I, Chaussade S, Kaddour N, Laquière A, Gaujoux S.

Frontline Gastroenterol. 2019 Jul;10(3):236-243. doi: 10.1136/flgastro-2018-100985. Epub 2018 Nov 27. PMID: 31281624

• 19 G nitinol needle versus 22 G needle for transduodenal endoscopic ultrasound-guided sampling of pancreatic solid masses: a randomized study.

Laquière A, Lefort C, Maire F, Aubert A, Gincul R, Prat F, Grandval P, Croizet O, Boulant J, Vanbiervliet G, Pénaranda G, Lecomte L, Napoléon B, Boustière C.

Endoscopy. 2019 May;51(5):436-443.

• Needle-based confocal laser endomicroscopy of pancreatic cystic lesions: a prospective multicenter validation study in patients with definite diagnosis.

Napoleon B, Palazzo M, Lemaistre AI, Caillol F, Palazzo L, Aubert A, Buscail L, Maire F, Morellon BM, Pujol B, Giovannini M.

Endoscopy. 2019 Sep;51(9):825-835. doi: 10.1055/a-0732-5356. Epub 2018 Oct 22.

• First Case of Radiation-Induced Diffuse Hemorrhagic Gastritis Successfully Treated with Intravenous Bevazicumab.

Maire F, Muller N, Lévy P.

Am J Gastroenterol. 2017 Aug;112(8):1349-1350. doi: 10.1038/ajg.2017.160. No abstract available. PMID: 28766568

• Socioeconomic Effect of Education on Pancreatic Cancer Risk in Western Europe: An Update on the EPIC Cohorts Study. 

Cirera L, Huerta JM, Chirlaque MD, Overvad K, Lindström M, Regnér S, Tjønneland A, Boutron-Ruault MC, Rebours V, Fagherazzi G, Katzke VA, Boeing H, Peppa E, Trichopoulou A, Valanou E, Palli D, Grioni S, Panico S, Tumino R, Ricceri F, van Gils C, Vermeulen RCH, Skeie G, Braaten T, Weiderpass E, Merino S, Sánchez MJ, Larrañaga N, Ardanaz E, Sund M, Khaw KT, Key TJ, Jenab M, Naudin S, Murphy N, Aune D, Ward H, Riboli E, Bueno-de-Mesquita B, Navarro C, Duell EJ. 

Cancer Epidemiol Biomarkers Prev. 2019 Jun;28(6):1089-1092. 

• Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition. 

Obón-Santacana M, Luján-Barroso L, Freisling H, Naudin S, Boutron-Ruault MC, Mancini FR, Rebours V, Kühn T, Katzke V, Boeing H, Tjønneland A, Olsen A, Overvad K, Lasheras C, Rodríguez-Barranco M, Amiano P, Santiuste C, Ardanaz E, Khaw KT, Wareham NJ, Schmidt JA, Aune D, Trichopoulou A, Thriskos P, Peppa E, Masala G, Grioni S, Tumino R, Panico S, Bueno-de-Mesquita B, Sciannameo V, Vermeulen R, Sonestedt E, Sund M, Weiderpass E, Skeie G, González CA, Riboli E, Duell EJ.

 Int J Cancer. 2019 May 20. 

• Temozolomide alone or combined to capecitabine for the treatment of advanced pancreatic NET. 

de Mestier L, Walter T, Evrard C, de Boissieu P, Hentic O, Cros J, Tougeron D, Lombard-Bohas C, Rebours V, Hammel P, Ruszniewski P. 

Neuroendocrinology. 2019 May 10. 

• GNAS but Not Extended RAS Mutations Spectrum are Associated with a Better Prognosis in Intraductal Pancreatic Mucinous Neoplasms. 

Gaujoux S, Parvanescu A, Cesaretti M, Silve C, Bieche I, Rebours V, Lévy P, Sauvanet A, Cros J. 

Ann Surg Oncol. 2019 Apr 25.

• Appropriateness of pancreatic resection in high-risk individuals for familial pancreatic ductal adenocarcinoma: a patient-level meta-analysis and proposition of the Beaujon score. 

de Mestier L, Muller M, Cros J, Vullierme MP, Vernerey D, Maire F, Dokmak S, Rebours V, Sauvanet A, Lévy P, Hammel P. 

United European Gastroenterol J. 2019 Apr;7(3):358-368.

• Non-branched microcysts of the pancreas on MR imaging of patients with pancreatic tumors who had pancreatectomy may predict the presence of pancreatic intraepithelial neoplasia (PanIN): a preliminary study. 

Vullierme MP, Menassa L, Couvelard A, Rebours V, Maire F, Ibrahim T, Cros J, Ruszniewski P, Sauvanet A, Levy P, Soyer P, Vilgrain V.

Eur Radiol. 2019 Apr 10.

• Comparison of temozolomide-capecitabine to 5-fluorouracile-dacarbazine in 247 patients with advanced digestive neuroendocrine tumors using propensity score analyses. 

de Mestier L, Walter T, Brixi H, Evrard C, Legoux JL, de Boissieu P, Hentic O, Cros J, Hammel P, Tougeron D, Lombard-Bohas C, Rebours V, Ruszniewski P, Cadiot G. 

Neuroendocrinology. 2019 Feb 13. 

• 19 G nitinol needle versus 22 G needle for transduodenal endoscopic ultrasound-guided sampling of pancreatic solid masses: a randomized study. 

Laquière A, Lefort C, Maire F, Aubert A, Gincul R, Prat F, Grandval P, Croizet O, Boulant J, Vanbiervliet G, Pénaranda G, Lecomte L, Napoléon B, Boustière C. 

Endoscopy 2019;51:436-443.

• Unmet Medical Needs in Pulmonary Neuroendocrine (Carcinoid) Neoplasms. 

Baudin E, Hayes AR, Scoazec JY, Filosso PL, Lim E, Kaltsas G, Frilling A, Chen J, Kos-Kudła B, Gorbunova V, Wiedenmann B, Nieveen van Dijkum E, Ćwikła JB, Falkerby J, Valle JW, Kulke MH, Caplin ME; ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants. 

Neuroendocrinology. 2019;108(1):7-17

• Unmet Needs in Appendiceal Neuroendocrine Neoplasms. 

Toumpanakis C, Fazio N, Tiensuu Janson E, Hörsch D, Pascher A, Reed N, O Apos Toole D, Nieveen van Dijkum E, Partelli S, Rinke A, Kos-Kudla B, Costa F, Pape UF, Grozinsky-Glasberg S, Scoazec JY; The ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants. 

Neuroendocrinology. 2019;108(1):37-44. 

• Colorectal Neuroendocrine Neoplasms: Areas of Unmet Need. 

Ramage JK, Valle JW, Nieveen van Dijkum EJM, Sundin A, Pascher A, Couvelard A, Kloeppel G; the ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants. 

Neuroendocrinology. 2019;108(1):45-53. 

• Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms.

Capdevila J, Bodei L, Davies P, Gorbounova V, Jensen RT, Knigge UP, Krejs GJ, Krenning E, O’Connor JM, Peeters M, Rindi G, Salazar R, Vullierme MP, Pavel ME; ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants. 

Neuroendocrinology. 2019;108(1):18-25

• Unmet Needs in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms (WHO G3).

Sorbye H, Baudin E, Borbath I, Caplin M, Chen J, Cwikla JB, Frilling A, Grossman A, Kaltsas G, Scarpa A, Welin S, Garcia-Carbonero R; ENETS 2016 Munich Advisory Board Participants. 

Neuroendocrinology. 2019;108(1):54-62. doi: 10.1159/000493318. Epub 2018 Aug 28.

• Pancreatic ductal deletion of Hnf1b disrupts exocrine homeostasis, leads to pancreatitis and facilitates tumorigenesis.

Quilichini E, Fabre M, Dirami T, Stedman A, De Vas M, Ozguc O, Pasek RC, Cereghini S, Morillon L, Guerra C, Couvelard A, Gannon M, Haumaitre C.

Cell Mol Gastroenterol Hepatol. 2019 Jun 20. 

• Kras and Lkb1 mutations synergistically induce intraductal papillary mucinous neoplasm derived from pancreatic duct cells.

Collet L, Ghurburrun E, Meyers N, Assi M, Pirlot B, Leclercq IA, Couvelard A, Komuta M, Cros J, Demetter P, Lemaigre FP, Borbath I, Jacquemin P.

Gut. 2019 Jun 1. pii: gutjnl-2018-318059. 

• Preclinical Evaluation of 68Ga-DOTA-NT-20.3: A Promising PET Imaging Probe To Discriminate Human Pancreatic Ductal Adenocarcinoma from Pancreatitis.

Prignon A, Provost C, Alshoukr F, Wendum D, Couvelard A, Barbet J, Forgez P, Talbot JN, Gruaz-Guyon A.

Mol Pharm. 2019 Jun 3;16(6):2776-2784. 

• O6-methylguanine-DNA methyltransferase (MGMT) status in neuroendocrine tumors: a randomized phase II study (MGMT-NET).

Lemelin A, Barritault M, Hervieu V, Payen L, Péron J, Couvelard A, Cros J, Scoazec JY, Bin S, Villeneuve L, Lombard-Bohas C, Walter T; MGMT-NET investigators.

Dig Liver Dis. 2019 Apr;51(4):595-599. 

• Prognostic Biomarkers in Pancreatic Cancer: Avoiding Errata When Using the TCGA Dataset.

Nicolle R, Raffenne J, Paradis V, Couvelard A, de Reynies A, Blum Y, Cros J.

Cancers (Basel). 2019 Jan 21;11(1). 

• Unmet Needs in Functional and Nonfunctional Pancreatic Neuroendocrine Neoplasms.

Jensen RT, Bodei L, Capdevila J, Couvelard A, Falconi M, Glasberg S, Kloppel G, Lamberts S, Peeters M, Rindi G, Rinke A, Rothmund M, Sundin A, Welin S, Fazio N; The ENETS 2016 Munich Advisory Board Participants; ENETS 2016 Munich Advisory Board Participants.

Neuroendocrinology. 2019;108(1):26-36. 

• Lesion-by-lesion Correlation Between Uptake at FDG PET and the Ki67 Proliferation Index in Resected Pancreatic Neuroendocrine Tumors

de Mestier L, Armani M, Cros J, Hentic O, Rebours V, Cadiot G, Sauvanet A, Couvelard A, Lebtahi R, Ruszniewski P. Dig Liver Dis. 2019 Jul 23. pii: S1590-8658(19)30680-2.

doi: 10.1016/j.dld.2019.06.022. [Epub ahead of print] PubMed PMID: 31350186.

• Endoscopic, Transanal, Laparoscopic, and Transabdominal Management of Rectal Neuroendocrine Tumors

de Mestier L, Lorenzo D, Fine C, Cros J, Hentic O, Walter T, Panis Y, Couvelard A, Cadiot G, Ruszniewski P. Best Pract Res Clin Endocrinol Metab. 2019 Jul 9:101293. doi: 10.1016/j.beem.2019.101293. [Epub ahead of print] Review. PubMed PMID: 31326374.

• Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms (MiNEN)

de Mestier L, Cros J. Ann Endocrinol (Paris). 2019 Jun;80(3):172-173. doi: 10.1016/j.ando.2019.04.006. Epub 2019 Apr 11. PubMed PMID: 31064662.

• Appropriateness of pancreatic resection in high-risk individuals for familial pancreatic ductal adenocarcinoma: a patient-level meta-analysis and proposition of the Beaujon score.

de Mestier L, Muller M, Cros J, Vullierme MP, Vernerey D, Maire F, Dokmak S, Rebours V, Sauvanet A, Lévy P, Hammel P. United European Gastroenterol J. 2019 Apr;7(3):358-368. doi: 10.1177/2050640618824910. Epub 2019 Jan 12. PubMed PMID: 31019704; PubMed Central PMCID: PMC6466755.

• Value of Tumor Growth Rate (TGR) as an Early Biomarker Predictor of Patients’ Outcome in Neuroendocrine Tumors (NET)

Lamarca A, Crona J, Ronot M, Opalinska M, Lopez Lopez C, Pezzutti D, Najran P, Carvhalo L, Franca Bezerra RO, Borg P, Vietti Violi N, Vidal Trueba H, de Mestier L, Schaefer N, Sundin A, Costa F, Pavel M, Dromain C; The GREPONET Study. Oncologist. 2019 Mar 25. pii: theoncologist.2018-0672. doi: 10.1634/theoncologist.2018-0672. [Epub ahead of print] PubMed PMID: 30910869.